Canine distemper is a viral disease and is highly. While puppies are at greatest risk, this virus can affect dogs of any. Symptoms vary but can include depression, fever, sneezing, coughing, nasal discharge, loss of appetite, vomiting and diarrhoea. Paralysis, fits and muscle tremors usually occur at a later stage of the disease. Treatment is generally ineffective. The recovery rate of dogs with distemper is very low. Dogs that do recover may suffer from permanent damage to the brain.